Review: Physical diagnostic tests have low diagnostic accuracy for meniscal lesions of the kneePDF
ACP J Club. 2002 May-Jun;136:113. doi:10.7326/ACPJC-2002-136-3-113
Scholten RJ, Devillé WL, Opstelten W, et al. The accuracy of physical diagnostic tests for assessing meniscal lesions of the knee: a meta-analysis. J Fam Pract. 2001 Nov;50:938-44. [PubMed ID: 11711009] (All 2002 articles were reviewed for relevancy, and abstracts were last revised in 2008.)
In patients with meniscal lesions of the knee, what is the diagnostic accuracy of physical diagnostic tests?
Studies were identified by searching MEDLINE (1966 to 1999) and EMBASE/Excerpta Medica (1988 to 1999) with terms describing knee joint, knee, menisci tibial, and effusion. Bibliographies of relevant studies were scanned.
2 reviewers independently selected studies that were published in English, French, German, or Dutch; reported the accuracy of ≥ 1 physical diagnostic test for the assessment of meniscal lesions of the knee; and used arthrotomy, arthroscopy, or magnetic resonance imaging (MRI) as the diagnostic standard. Studies were excluded if they did not have a reference group, included only persons with positive test results, pertained to cadavers only, or considered physical examination under anesthesia only.
2 reviewers independently assessed the quality of study methods and extracted data on the spectrum of lesions, number of patients, patients’ ages, duration of symptoms, prevalence, sensitivity, specificity, and likelihood ratios.
13 studies (2231 patients) were included. The index test and diagnostic standard were assessed blindly in 2 studies. 9 studies used arthroscopy and 1 study used MRI as the diagnostic standard. Verification bias (i.e., patients with an abnormal physical test finding had a greater likelihood of receiving the diagnostic standard) was present in most studies. The Table shows the ranges for sensitivity, specificity, and likelihood ratios for the joint effusion test (4 studies), the McMurray test (11 studies), the joint line tenderness test (13 studies), and the Apley compression test (4 studies).
In patients with meniscal lesions of the knee, physical diagnostic tests have low diagnostic accuracy.
Source of funding: No external funding.
For correspondence: Dr. R.J.P.M. Scholten, Dutch Cochrane Centre, Amsterdam, The Netherlands. E-mail R.J.Scholten@AMC.UvA.NL.
Table. Test characteristics for diagnosing meniscal lesions of the knee*
|Tests||Number of studies||Sensitivity range||Specificity range||+LR range||−LR range|
|Joint effusion||4||20% to 53%||54% to 100%||0.8 to ∞||0.7 to 1.1|
|McMurray test||11||10% to 66%||57% to 98%||1.5 to 9.5||0.4 to 0.9|
|Joint line tenderness||13||28% to 95%||5% to 95%||0.8 to 14.9||0.2 to 2.1|
|Apley compression test||4||16% to 58%||80% to 99%||0.8 to 19.5||0.5 to 1.1|
*Diagnostic terms defined in Glossary.
Can a primary care practitioner use the patient history and physical examination to correctly identify those with traumatic knee pain who would benefit from surgical intervention? In an excellent meta-analysis, Scholten and colleagues provide evidence that joint tenderness or swelling does not predict the presence or absence of a torn meniscus, and a positive McMurray test result is minimally predictive of a meniscal tear. Other issues relating to the authors’ research question require further attention.
First, most studies did not involve primary care providers. This omission biases the results toward a higher prevalence of meniscal tears and does not tell us whether primary practitioners do an examination similar to specialists. Second, the predictive value of such key questions in the patient’s history as locking of the knee with flexion, the motion of injury, giving way of the knee, and knee swelling remains elusive. Third, methodologic flaws may bias results. In 11 of 13 studies, the physical examination and the diagnostic standard (arthroscopy and MRI) were not assessed blindly, and patients with clinical suspicion of a meniscal lesion were more likely to have had surgery or an MRI. Finally, we do not know whether any test distinguishes a large traumatic tear (which will benefit from surgery) from a degenerative tear (which will respond to conservative management).
Should a primary provider continue to use joint effusion, tenderness, or a McMurray test in their physical examination? Until a large, well-controlled, prospective study involving primary care patients looks at the predictive power of both the patient history and the physical examination, we do not know for sure. In the meantime, it appears that physical examination is useful only when combined with the patient’s history. For example, a 35-year-old patient with an acute twisting injury, painful locking, and giving way has a greater chance of having a large, acute, surgically correctable meniscal tear than is a 56-year-old patient who notes that a trivial squat produced pain and giving way. In the 35-year-old patient, a positive McMurray test result increases the likelihood of surgical benefit, whereas in the 56-year-old patient it adds no information.
Stanford Shoor, MD
Kaiser Santa Clara Medical Center
Santa Clara, California, USA
1. Stratford PW, Binkley J. A review of the McMurray test: definition, interpretation, and clinical usefulness. J Orthop Sports Phys Ther. 1995;22:116-20. [PubMed ID: 8535469]
2. Hegedus EJ, Cook C, Hasselblad V, Goode A, McCrory DC. Physical examination tests for assessing a torn meniscus in the knee: a systematic review with meta-analaysis. J Orthop Sports Phys Ther. 2007;37:541-50. [PubMed ID: 17939613]